150 Beach Road, #25-02 Gateway West, Singapore 189720.
Phone : +65 6392 2643
Email : sales@ymc.sg
150 Beach Road, #25-02 Gateway West, Singapore 189720.
Phone : +65 6392 2643
Email : sales@ymc.sg

Alcyon SFC

Alcyon SFC

Alcyon SFC columns are Supercritical Fluid Chromatography (SFC) columns available with chiral or achiral stationary phases. The low viscosity of supercritical carbon dioxide enables analytical separations that are 3–5 times faster than those for normal-phase HPLC. High resolution and reduced solvent consumption are achieved.

Catalogue Download Link
Column care and use instruction download link
https://www.ymc.co.jp/data/download/AlcyonSFC_Amylose-SA_Cellulose-SB_Cellulose-SC_E.pdf
https://www.ymc.co.jp/data/download/AlcyonSFC_Cellulose-SJ_E.pdf
https://www.ymc.co.jp/data/download/AlcyonSFC_Cellulose-SZ_E.pdf
https://www.ymc.co.jp/data/download/AlcyonSFC_Amylose-C-CNeo_Cellulose-C_E.pdf
https://www.ymc.co.jp/data/download/AlcyonSFC_achiral_E.pdf

Alcyon SFC

Alcyon SFC columns are Supercritical Fluid Chromatography (SFC) columns available with chiral or achiral stationary phases. The low viscosity of supercritical carbon dioxide enables analytical separations that are 3–5 times faster than those for normal-phase HPLC. High resolution and reduced solvent consumption are achieved.

Catalogue Download Link
Column care and use instruction download link

Specification:

Specification:

Specification:

Faster separation with high resolution

Faster chiral separation of trans-Stilbene oxide is achieved using supercritical fluid chromatography compared with HPLC separation. The lower viscosity and larger diffusion coefficient of the supercritical fluid provide rapid separation of both chiral and achiral compounds.

SFC
Column Alcyon SFC CSP Amylose-C Neo
5 µm, 250 X 4.6 mmI.D.
Eluent CO2/methanol (80/20)
Flow rate 3.0 mL/min
Temperature 40°C
Detection UV at 220 nm
Back pressure 13.8 MPa (2000 psi)
HPLC
Column CHIRAL ART Amylose-C Neo
5 µm, 250 X 4.6 mmI.D.
Eluent n-hexane/2-propanol (90/10)
Flow rate 1.0 mL/min
Temperature 25°C
Detection UV at 230 nm

 

Efficient SFC preparative separation of flavanone

Compared with normal HPLC, Alcyon SFC column shows excellent peak shapes, even with faster separations without compromising the purity and yield. As a result, Alcyon SFC columns offer purification with higher efficiency owing to lower solvent consumption.

 

SFC Conditions
Column Alcyon SFC CSP Amylose-C
5µm, 250 X 20 mml.D.
Eluent CO2/methanol (80/20)
Flow rate 60 mL/min
Temperature 30°C
Detection UV at 280 nm
Back pressure 15 MPa (2180 psi)
Injection 1.5 mL (20 mg/mL)
HPLC Conditions
Column CHIRAL ART Amylose-C
5µm, 250 X 20 mml.D.
Eluent n-hexane/ethanol (90/10)
Flow rate 20 mL/min
Temperature ambient
Detection UV at 220 nm
Injection 3 mL (20 mg/mL)

 

Faster separation with high resolution

Faster chiral separation of trans-Stilbene oxide is achieved using supercritical fluid chromatography compared with HPLC separation. The lower viscosity and larger diffusion coefficient of the supercritical fluid provide rapid separation of both chiral and achiral compounds.

SFC
Column Alcyon SFC CSP Amylose-C Neo
5 µm, 250 X 4.6 mmI.D.
Eluent CO2/methanol (80/20)
Flow rate 3.0 mL/min
Temperature 40°C
Detection UV at 220 nm
Back pressure 13.8 MPa (2000 psi)
HPLC
Column CHIRAL ART Amylose-C Neo
5 µm, 250 X 4.6 mmI.D.
Eluent n-hexane/2-propanol (90/10)
Flow rate 1.0 mL/min
Temperature 25°C
Detection UV at 230 nm

 

Efficient SFC preparative separation of flavanone

Compared with normal HPLC, Alcyon SFC column shows excellent peak shapes, even with faster separations without compromising the purity and yield. As a result, Alcyon SFC columns offer purification with higher efficiency owing to lower solvent consumption.

 

SFC Conditions
Column Alcyon SFC CSP Amylose-C
5µm, 250 X 20 mml.D.
Eluent CO2/methanol (80/20)
Flow rate 60 mL/min
Temperature 30°C
Detection UV at 280 nm
Back pressure 15 MPa (2180 psi)
Injection 1.5 mL (20 mg/mL)
HPLC Conditions
Column CHIRAL ART Amylose-C
5µm, 250 X 20 mml.D.
Eluent n-hexane/ethanol (90/10)
Flow rate 20 mL/min
Temperature ambient
Detection UV at 220 nm
Injection 3 mL (20 mg/mL)

 

Faster separation with high resolution

Faster chiral separation of trans-Stilbene oxide is achieved using supercritical fluid chromatography compared with HPLC separation. The lower viscosity and larger diffusion coefficient of the supercritical fluid provide rapid separation of both chiral and achiral compounds.

SFC
Column Alcyon SFC CSP Amylose-C Neo
5 µm, 250 X 4.6 mmI.D.
Eluent CO2/methanol (80/20)
Flow rate 3.0 mL/min
Temperature 40°C
Detection UV at 220 nm
Back pressure 13.8 MPa (2000 psi)
HPLC
Column CHIRAL ART Amylose-C Neo
5 µm, 250 X 4.6 mmI.D.
Eluent n-hexane/2-propanol (90/10)
Flow rate 1.0 mL/min
Temperature 25°C
Detection UV at 230 nm

 

Efficient SFC preparative separation of flavanone

Compared with normal HPLC, Alcyon SFC column shows excellent peak shapes, even with faster separations without compromising the purity and yield. As a result, Alcyon SFC columns offer purification with higher efficiency owing to lower solvent consumption.

 

SFC Conditions
Column Alcyon SFC CSP Amylose-C
5µm, 250 X 20 mml.D.
Eluent CO2/methanol (80/20)
Flow rate 60 mL/min
Temperature 30°C
Detection UV at 280 nm
Back pressure 15 MPa (2180 psi)
Injection 1.5 mL (20 mg/mL)
HPLC Conditions
Column CHIRAL ART Amylose-C
5µm, 250 X 20 mml.D.
Eluent n-hexane/ethanol (90/10)
Flow rate 20 mL/min
Temperature ambient
Detection UV at 220 nm
Injection 3 mL (20 mg/mL)