150 Beach Road, #25-02 Gateway West, Singapore 189720.
150 Beach Road, #25-02 Gateway West, Singapore 189720.

Dynamic Axial Compression (DAC) Columns

Dynamic Axial Compression (DAC) Columns

YMC DAC columns are automated self packing columns suitable for laboratory-, pilot- and industrial-scale and they are cost-effective with refill of packing material. Three versions, i.e. DAD, DAU and DAR are available. The downward cylinder driving direction of DAD enables easy unpacking process while DAU series have compact design with upward cylinder driving direction. DAR series come with rotatable custom-designed. Superior column performance, durability and reproducibility are achieved with constant pressurization (Axial Compression Technology).

Dynamic Axial Compression (DAC) Columns

YMC DAC columns are automated self packing columns suitable for laboratory-, pilot- and industrial-scale and they are cost-effective with refill of packing material. Three versions, i.e. DAD, DAU and DAR are available. The downward cylinder driving direction of DAD enables easy unpacking process while DAU series have compact design with upward cylinder driving direction. DAR series come with rotatable custom-designed. Superior column performance, durability and reproducibility are achieved with constant pressurization (Axial Compression Technology).

Specification:

Specification:

Specification:

Prevention of voids by constant pressurization

In packing operation of axial compression columns, pressurizing by cylinder followed by loading slurry into columns can create homogenously packed column bed. This will prevent void or crack which is seen in conventional packed columns. This results in high durability and long column life in axial compression columns.

 

Optional slurry container permits automated packing procedures

The slurry container provides an excellent distribution of packing material and allows for a "homogenous" slurry that can be automatically loaded into the DAU / DAD column by simply switching a valve. Throughout the operation from slurry preparation to filling slurry, safety and hygiene can be achieved.

 

Seamless scale-up

The chromatogram on the right is a scale-up example from an analytical 4.6 mm I.D. column to a 50 mm I.D. DAC column. Very similar separation pattern in analytical scale is also reproducible at the preparative scale.

  1. Cytchrome C (MW 12,400)
  2. Insulin (MW 5,700)
  3. Lysozyme (MW 14,400)
  4. α-Lactalbumin (MW 14,200)
  5. Myoglobin (MW 17,000)

 

Analytical

Column YMC-Pack C8;
(5 µm, 200 Å) 150 x 4.6 mml.D.
Flow rate 0.8 mL/min

 

Preparative

Column YMC*GEL C8
(10 µm, 200 Å) 150 x 50 mml.D.
Eluent A) water/TFA (100/0.1)
B) acetonitrile/TFA (100/0.1)
25-60%B (o-20 min)
Flow rate 100 mL/min
Temperature 37°C
Detection UV at 220 nm

Prevention of voids by constant pressurization

In packing operation of axial compression columns, pressurizing by cylinder followed by loading slurry into columns can create homogenously packed column bed. This will prevent void or crack which is seen in conventional packed columns. This results in high durability and long column life in axial compression columns.

 

Optional slurry container permits automated packing procedures

The slurry container provides an excellent distribution of packing material and allows for a "homogenous" slurry that can be automatically loaded into the DAU / DAD column by simply switching a valve. Throughout the operation from slurry preparation to filling slurry, safety and hygiene can be achieved.

 

Seamless scale-up

The chromatogram on the right is a scale-up example from an analytical 4.6 mm I.D. column to a 50 mm I.D. DAC column. Very similar separation pattern in analytical scale is also reproducible at the preparative scale.

  1. Cytchrome C (MW 12,400)
  2. Insulin (MW 5,700)
  3. Lysozyme (MW 14,400)
  4. α-Lactalbumin (MW 14,200)
  5. Myoglobin (MW 17,000)

 

Analytical

Column YMC-Pack C8;
(5 µm, 200 Å) 150 x 4.6 mml.D.
Flow rate 0.8 mL/min

 

Preparative

Column YMC*GEL C8
(10 µm, 200 Å) 150 x 50 mml.D.
Eluent A) water/TFA (100/0.1)
B) acetonitrile/TFA (100/0.1)
25-60%B (o-20 min)
Flow rate 100 mL/min
Temperature 37°C
Detection UV at 220 nm

Prevention of voids by constant pressurization

In packing operation of axial compression columns, pressurizing by cylinder followed by loading slurry into columns can create homogenously packed column bed. This will prevent void or crack which is seen in conventional packed columns. This results in high durability and long column life in axial compression columns.

 

Optional slurry container permits automated packing procedures

The slurry container provides an excellent distribution of packing material and allows for a "homogenous" slurry that can be automatically loaded into the DAU / DAD column by simply switching a valve. Throughout the operation from slurry preparation to filling slurry, safety and hygiene can be achieved.

 

Seamless scale-up

The chromatogram on the right is a scale-up example from an analytical 4.6 mm I.D. column to a 50 mm I.D. DAC column. Very similar separation pattern in analytical scale is also reproducible at the preparative scale.

  1. Cytchrome C (MW 12,400)
  2. Insulin (MW 5,700)
  3. Lysozyme (MW 14,400)
  4. α-Lactalbumin (MW 14,200)
  5. Myoglobin (MW 17,000)

 

Analytical

Column YMC-Pack C8;
(5 µm, 200 Å) 150 x 4.6 mml.D.
Flow rate 0.8 mL/min

 

Preparative

Column YMC*GEL C8
(10 µm, 200 Å) 150 x 50 mml.D.
Eluent A) water/TFA (100/0.1)
B) acetonitrile/TFA (100/0.1)
25-60%B (o-20 min)
Flow rate 100 mL/min
Temperature 37°C
Detection UV at 220 nm

Specification:

Specification:

Specification:

Prevention of voids by constant pressurization

In packing operation of axial compression columns, pressurizing by cylinder followed by loading slurry into columns can create homogenously packed column bed. This will prevent void or crack which is seen in conventional packed columns. This results in high durability and long column life in axial compression columns.

 

Optional slurry container permits automated packing procedures

The slurry container provides an excellent distribution of packing material and allows for a "homogenous" slurry that can be automatically loaded into the DAU / DAD column by simply switching a valve. Throughout the operation from slurry preparation to filling slurry, safety and hygiene can be achieved.

 

Seamless scale-up

The chromatogram on the right is a scale-up example from an analytical 4.6 mm I.D. column to a 50 mm I.D. DAC column. Very similar separation pattern in analytical scale is also reproducible at the preparative scale.

  1. Cytchrome C (MW 12,400)
  2. Insulin (MW 5,700)
  3. Lysozyme (MW 14,400)
  4. α-Lactalbumin (MW 14,200)
  5. Myoglobin (MW 17,000)

 

Analytical

Column YMC-Pack C8;
(5 µm, 200 Å) 150 x 4.6 mml.D.
Flow rate 0.8 mL/min

 

Preparative

Column YMC*GEL C8
(10 µm, 200 Å) 150 x 50 mml.D.
Eluent A) water/TFA (100/0.1)
B) acetonitrile/TFA (100/0.1)
25-60%B (o-20 min)
Flow rate 100 mL/min
Temperature 37°C
Detection UV at 220 nm

Prevention of voids by constant pressurization

In packing operation of axial compression columns, pressurizing by cylinder followed by loading slurry into columns can create homogenously packed column bed. This will prevent void or crack which is seen in conventional packed columns. This results in high durability and long column life in axial compression columns.

 

Optional slurry container permits automated packing procedures

The slurry container provides an excellent distribution of packing material and allows for a "homogenous" slurry that can be automatically loaded into the DAU / DAD column by simply switching a valve. Throughout the operation from slurry preparation to filling slurry, safety and hygiene can be achieved.

 

Seamless scale-up

The chromatogram on the right is a scale-up example from an analytical 4.6 mm I.D. column to a 50 mm I.D. DAC column. Very similar separation pattern in analytical scale is also reproducible at the preparative scale.

  1. Cytchrome C (MW 12,400)
  2. Insulin (MW 5,700)
  3. Lysozyme (MW 14,400)
  4. α-Lactalbumin (MW 14,200)
  5. Myoglobin (MW 17,000)

 

Analytical

Column YMC-Pack C8;
(5 µm, 200 Å) 150 x 4.6 mml.D.
Flow rate 0.8 mL/min

 

Preparative

Column YMC*GEL C8
(10 µm, 200 Å) 150 x 50 mml.D.
Eluent A) water/TFA (100/0.1)
B) acetonitrile/TFA (100/0.1)
25-60%B (o-20 min)
Flow rate 100 mL/min
Temperature 37°C
Detection UV at 220 nm

Prevention of voids by constant pressurization

In packing operation of axial compression columns, pressurizing by cylinder followed by loading slurry into columns can create homogenously packed column bed. This will prevent void or crack which is seen in conventional packed columns. This results in high durability and long column life in axial compression columns.

 

Optional slurry container permits automated packing procedures

The slurry container provides an excellent distribution of packing material and allows for a "homogenous" slurry that can be automatically loaded into the DAU / DAD column by simply switching a valve. Throughout the operation from slurry preparation to filling slurry, safety and hygiene can be achieved.

 

Seamless scale-up

The chromatogram on the right is a scale-up example from an analytical 4.6 mm I.D. column to a 50 mm I.D. DAC column. Very similar separation pattern in analytical scale is also reproducible at the preparative scale.

  1. Cytchrome C (MW 12,400)
  2. Insulin (MW 5,700)
  3. Lysozyme (MW 14,400)
  4. α-Lactalbumin (MW 14,200)
  5. Myoglobin (MW 17,000)

 

Analytical

Column YMC-Pack C8;
(5 µm, 200 Å) 150 x 4.6 mml.D.
Flow rate 0.8 mL/min

 

Preparative

Column YMC*GEL C8
(10 µm, 200 Å) 150 x 50 mml.D.
Eluent A) water/TFA (100/0.1)
B) acetonitrile/TFA (100/0.1)
25-60%B (o-20 min)
Flow rate 100 mL/min
Temperature 37°C
Detection UV at 220 nm

Specification:

Specification:

Specification:

Prevention of voids by constant pressurization

In packing operation of axial compression columns, pressurizing by cylinder followed by loading slurry into columns can create homogenously packed column bed. This will prevent void or crack which is seen in conventional packed columns. This results in high durability and long column life in axial compression columns.

 

Optional slurry container permits automated packing procedures

The slurry container provides an excellent distribution of packing material and allows for a "homogenous" slurry that can be automatically loaded into the DAU / DAD column by simply switching a valve. Throughout the operation from slurry preparation to filling slurry, safety and hygiene can be achieved.

 

Seamless scale-up

The chromatogram on the right is a scale-up example from an analytical 4.6 mm I.D. column to a 50 mm I.D. DAC column. Very similar separation pattern in analytical scale is also reproducible at the preparative scale.

  1. Cytchrome C (MW 12,400)
  2. Insulin (MW 5,700)
  3. Lysozyme (MW 14,400)
  4. α-Lactalbumin (MW 14,200)
  5. Myoglobin (MW 17,000)

 

Analytical

Column YMC-Pack C8;
(5 µm, 200 Å) 150 x 4.6 mml.D.
Flow rate 0.8 mL/min

 

Preparative

Column YMC*GEL C8
(10 µm, 200 Å) 150 x 50 mml.D.
Eluent A) water/TFA (100/0.1)
B) acetonitrile/TFA (100/0.1)
25-60%B (o-20 min)
Flow rate 100 mL/min
Temperature 37°C
Detection UV at 220 nm

Prevention of voids by constant pressurization

In packing operation of axial compression columns, pressurizing by cylinder followed by loading slurry into columns can create homogenously packed column bed. This will prevent void or crack which is seen in conventional packed columns. This results in high durability and long column life in axial compression columns.

 

Optional slurry container permits automated packing procedures

The slurry container provides an excellent distribution of packing material and allows for a "homogenous" slurry that can be automatically loaded into the DAU / DAD column by simply switching a valve. Throughout the operation from slurry preparation to filling slurry, safety and hygiene can be achieved.

 

Seamless scale-up

The chromatogram on the right is a scale-up example from an analytical 4.6 mm I.D. column to a 50 mm I.D. DAC column. Very similar separation pattern in analytical scale is also reproducible at the preparative scale.

  1. Cytchrome C (MW 12,400)
  2. Insulin (MW 5,700)
  3. Lysozyme (MW 14,400)
  4. α-Lactalbumin (MW 14,200)
  5. Myoglobin (MW 17,000)

 

Analytical

Column YMC-Pack C8;
(5 µm, 200 Å) 150 x 4.6 mml.D.
Flow rate 0.8 mL/min

 

Preparative

Column YMC*GEL C8
(10 µm, 200 Å) 150 x 50 mml.D.
Eluent A) water/TFA (100/0.1)
B) acetonitrile/TFA (100/0.1)
25-60%B (o-20 min)
Flow rate 100 mL/min
Temperature 37°C
Detection UV at 220 nm

Prevention of voids by constant pressurization

In packing operation of axial compression columns, pressurizing by cylinder followed by loading slurry into columns can create homogenously packed column bed. This will prevent void or crack which is seen in conventional packed columns. This results in high durability and long column life in axial compression columns.

 

Optional slurry container permits automated packing procedures

The slurry container provides an excellent distribution of packing material and allows for a "homogenous" slurry that can be automatically loaded into the DAU / DAD column by simply switching a valve. Throughout the operation from slurry preparation to filling slurry, safety and hygiene can be achieved.

 

Seamless scale-up

The chromatogram on the right is a scale-up example from an analytical 4.6 mm I.D. column to a 50 mm I.D. DAC column. Very similar separation pattern in analytical scale is also reproducible at the preparative scale.

  1. Cytchrome C (MW 12,400)
  2. Insulin (MW 5,700)
  3. Lysozyme (MW 14,400)
  4. α-Lactalbumin (MW 14,200)
  5. Myoglobin (MW 17,000)

 

Analytical

Column YMC-Pack C8;
(5 µm, 200 Å) 150 x 4.6 mml.D.
Flow rate 0.8 mL/min

 

Preparative

Column YMC*GEL C8
(10 µm, 200 Å) 150 x 50 mml.D.
Eluent A) water/TFA (100/0.1)
B) acetonitrile/TFA (100/0.1)
25-60%B (o-20 min)
Flow rate 100 mL/min
Temperature 37°C
Detection UV at 220 nm

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150 Beach Road, #25-02 Gateway West, Singapore 189720.

Tel : +65 6392 2643

Fax : +65 6392 2856

Email : sales@ymc.sg

YMC Singapore Tradelinks Pte. Ltd.

150 Beach Road, #25-02 Gateway West, Singapore 189720.

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